In this Issue
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The
OV-Watch® Newsletter |
Vol. 5, Iss. 7 |
September 2009 |
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OV-Watch is now being stocked in Retail Pharmacies. Click on the ad below for a store near you.
OV-Watch is stocked in the following stores:
Click on the ad above for a complete listing
| New York: |
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Rockville Centre Pharmacy |
516-764-6161 |
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Kings Pharmacy |
718-230-3535 |
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Metro Drugs |
718-431-8000 |
| California: |
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Roxsan Pharmacy |
310-273-1644 |
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MDR Encino Pharmacy |
818-788-5858 |
| Ohio: |
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Barron Pharmacy |
216-360-0500 |
| Georgia: |
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Concord Pharmacy |
404-781-2229 |
Please call your specific store to check for stock.
Tell Your Doctor about OV-Watch
Please share the news with your doctors! If you are using OV-Watch or want your physicians support to use OV-Watch or if you just
want them to have information about OV-Watch, send them our latest clinical presentation entitled, "Scientific Basis and Clinical
Experience with OV-Watch" presentation by G. Wright Bates, Jr. M.D. click here
for the full presentation or copy and paste this
link: http://www.ovwatch.com/videos/ScientificBasis&ClinicalExpPresentation.asp.
You can also email us at professionals@ovwatch.com.
Customer Service Hours
OV-Watch now has new customer service hours. Monday - Friday 10:00 am to 3:00 pm Est.
You can always email us at customercare@ovwatch.com or
lexieann@ovwatch.com and we will get back to you promptly. If you need to
speak to us please leave your phone number and the best time to reach you and we will.
Fertility Friend
You can now track your OV-Watch fertile and ovulation days on
fertility friend.
If you use another calendar to track your fertility tell us
so we can get OV-Watch added too.
We want to hear from you!
Do you have questions or comments for OV-Watch email us!
We want to know what you would like to see in the next newsletter.
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Men who make no sperm at all and women with a sterilising disorder may both owe their infertility to the same surprising origin:
a weakness in the Y chromosome that makes men male.
Scientists have discovered that a genetic proof-reading process that normally protects the Y chromosome against harmful mutations
can itself inflict damage, triggering a wide range of sexual disorders that affect both genders.
This vulnerability appears to underlie many cases of male infertility, in which a man lacks genes on the Y chromosome that are
essential to sperm production, but it can also cause intersex conditions and even a sex development disorder that only affects
females.
It is likely to be a cause of Turner syndrome, a condition in which women have only one X chromosome instead of the normal two,
with symptoms that usually include short stature and infertility.
While it has generally been thought that women with Turner syndrome have lost a second X chromosome, the new research suggests
that some may actually have started out as chromosomal males, in whom the Y chromosome disintegrated soon after conception.
Y chromosomes that become defective in this way can also cause other disorders of sexual development, such as cases in which
people have both an ovary and a testis, or have female genitalia but male chromosomes.
David Page, of the Whitehead Institute for Biological Research at the Massachusetts Institute of Technology, who led the research,
said affected individuals “range from a man with no sperm who is otherwise healthy, to someone raised as a boy who is later found
to have an ovary on one side, to a girl or woman with Turner syndrome. These wildly different outcomes result from the very same
starting point.”
In the new research, which is
published in the journal Cell, Dr Page’s team investigated a process by which the Y chromosome protects
itself against accumulated DNA damage.
Unlike all the other 23 human chromosomes, including the X, the Y never exists in matching pair, and thus lacks a partner chromosome
with which to swap DNA to correct copying errors. It has thus evolved a different way of proof-reading its genetic code during
cell division.
Many of the Y chromosome’s key genetic sequences exist in palindromes, where the sequence is its own mirror image so it reads the same
way in reverse. When the chromosome is copied, key genes can thus be checked against these mirror images to ensure faithful replication.
Dr Page’s team has now discovered that this process, which normally protects the Y chromosome, can also damage it by turning the entire
chromosome into a palindrome. These abnormal Y chromosomes are highly unstable, so that parts can break off or the whole structure can
disintegrate.
If an egg is fertilised by a sperm carrying an abnormal Y chromosome, several possibilities can follow. If the Y chromosome disintegrates
altogether, the result may be Turner syndrome: an embryo with one X chromosome but no other sex chromosome at all.
If genes that are critical to sperm development are lost from the abnormal chromosome, the resulting embryo will grow into a man who makes
no sperm and is infertile. The loss of other parts of the chromosome can lead to intersex disorders.
Dr Page, who also led the team that first sequenced the DNA of the Y chromosome and discovered the palindromic protection mechanism,
said: “This is the sequel to the Y chromosome palindrome story.”
Professor Robin Lovell-Badge, of the National Institute for Medical Research in London, who discovered the gene on the Y chromosome that
determines male sex, said: “I think this is an excellent piece of work, not least because it accounts for so many observations of human
infertility, sex reversal and Turner syndrome as well as human Y chromosome biology.”
See the full article
here.
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Pregnant Pharmacist, CA
My husband, who is a physician, and I had been trying to conceive for over a year. I had been getting regular periods but
since it was taking awhile to conceive, they referred me to a Reproductive Endocrinologist. They weren't sure if I had PCOS.
2 ovarian scans on different months revealed that I ovulate but my ovaries looked a "little polycystic." They put me on
metformin after I had requested a trial. We tried that for a few months and began a round of Clomid with the accompanying
ovarian ultrasound and HCG trigger shot with no luck. I started researching other alternatives on the internet when I read
an article about Trista Sutter (the Bachelorette) talking about her second baby and the difficulty she had in conceiving
her first child. She said that she was eventually able to conceive using a watch. Intrigued, I did more research on the
internet and found the Ov-Watch. My husband, an "evidence-based" medical professional, was highly skeptical when I told him
that I was going to spend all this money on a watch. I reminded him that it was cheaper than pursuing our next step, IUI or
possibly IVF in the future. I bought the watch and literally after the first month of using it, we got pregnant! The first
words out of his mouth were, "how about that watch!" We can't stop talking about it and would recommend it to anyone trying
to get pregnant. I am only the second patient that my physician has seen who has tried it and both of us have gotten pregnant.
I think that she, too, may be a believer!
You can submit your OV-Watch success story
here or send
me the link to your blog if you succeeded using OV-Watch or just trying. We want to hear from you!
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Exchange Program
If you are a current customer with the old style OV-Watch, you can exchange it for our new style OV-Watch at an
incredible discount. If you purchase a Starter Kit 1 receive $50 off or purchase a Value Kit 4 and receive $99 off.
Please call 1-866-ovwatch and tell the customer service agent you would like to participate in the exchange program.
This is our way of saying thanks for being a customer.
This special cannot be combined with any other offers.
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OV-Watch is now on Facebook!
Join us
on our fan page & also check our
private group where you can
discuss your fertility and the use of OV-Watch
OV-Watch is now on Twitter
Come follow us at http://twitter.com/OV_Watch
OV-Watch Blinkies
OV-Watch is pleased to offer our collection of "blinkies" for all our moms-to-be
and mom's. You can add to your e-mail or signatures in any chatroom and help spread the word about OV-Watch. To access the
collection,
- Go
to www.photobucket.com.
- Enter user name: ovwatch.
- Enter password: ovwatch2007.
- In the middle of the page, click on "ov-watch blinkies."
- Select your favorite/s and use them.
Message Board
Join us on our free message board and talk to other members about trying to get pregnant and other fun
topics. www.mybabychat.com
Ask an OV-Watch Mom
Ask
an OV-Watch Mom allows you to get answers from someone who's been there. If you're considering OV-Watch to get pregnant, we offer this service free of charge.
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